VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

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Hepacivirus C

Family: Flaviviridae

Receptor: EGFR

Receptor EGFR information

Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0035 2021.04 10X Genomics Duodenum Normal 1482 Link
Vthunter_0036 2021.04 10X Genomics Esophagus Normal 24581 Link
Vthunter_0037 2021.04 10X Genomics Heart Normal 12958 Link
Vthunter_0038 2021.04 10X Genomics Kidney Normal 4481 Link
Vthunter_0039 2021.04 10X Genomics LargeIntestine Normal 3328 Link
Vthunter_0040 2021.04 10X Genomics Liver Normal 5694 Link
Vthunter_0041 2021.04 10X Genomics Lung Normal 13720 Link
Vthunter_0042 2021.04 10X Genomics Spleen Normal 3207 Link
Vthunter_0043 2021.04 10X Genomics Stomach Normal 12485 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of EGFR in human tissues   [NCBI]

Expression: Broad expression in placenta (RPKM 36.6), skin (RPKM 15.6) and 22 other tissues?

Protein expression of EGFR in human tissues   [Proteinatlas]